Updated at 1:45 p.m. ET
At least two people were killed and at least 100 people were injured early Sunday morning when an Amtrak train derailed after colliding with a freight train in South Carolina.
The derailment happened in Cayce, outside of South Carolina's capital of Columbia.
Amtrak said a train going between New York and Miami "came in contact" with a CSX freight train at about 2:35 Sunday morning.